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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HPS3 All Species: 7.58
Human Site: S287 Identified Species: 20.83
UniProt: Q969F9 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969F9 NP_115759.2 1004 113736 S287 A D E K R K Y S H F Q H L L Y
Chimpanzee Pan troglodytes XP_001139589 1004 113767 S287 A D E K R K Y S H F Q H L L Y
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542830 651 73399
Cat Felis silvestris
Mouse Mus musculus Q91VB4 1002 113133 Y285 L E D E K V K Y L R V R H L L
Rat Rattus norvegicus NP_001101134 1002 113514 Y285 L E D E K V K Y L H V Q H L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422849 1007 114181 F292 S T E D K K H F E V Q Y L L F
Frog Xenopus laevis NP_001082416 998 112772 R287 S D F Q N C T R V C H L L Y R
Zebra Danio Brachydanio rerio NP_001071267 524 58109
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120488 982 111407 I272 M N N Q D D N I I L Q G A N S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 56.6 N.A. 80.9 80.9 N.A. N.A. 58.9 53.5 23.2 N.A. N.A. 21 N.A. N.A.
Protein Similarity: 100 99.6 N.A. 60.4 N.A. 90.1 89.9 N.A. N.A. 76.3 72.5 35.1 N.A. N.A. 40.9 N.A. N.A.
P-Site Identity: 100 100 N.A. 0 N.A. 6.6 6.6 N.A. N.A. 33.3 13.3 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 N.A. 0 N.A. 33.3 33.3 N.A. N.A. 66.6 26.6 0 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % A
% Cys: 0 0 0 0 0 12 0 0 0 12 0 0 0 0 0 % C
% Asp: 0 34 23 12 12 12 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 23 34 23 0 0 0 0 12 0 0 0 0 0 0 % E
% Phe: 0 0 12 0 0 0 0 12 0 23 0 0 0 0 12 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % G
% His: 0 0 0 0 0 0 12 0 23 12 12 23 23 0 0 % H
% Ile: 0 0 0 0 0 0 0 12 12 0 0 0 0 0 0 % I
% Lys: 0 0 0 23 34 34 23 0 0 0 0 0 0 0 0 % K
% Leu: 23 0 0 0 0 0 0 0 23 12 0 12 45 56 23 % L
% Met: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 12 12 0 12 0 12 0 0 0 0 0 0 12 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 23 0 0 0 0 0 0 45 12 0 0 0 % Q
% Arg: 0 0 0 0 23 0 0 12 0 12 0 12 0 0 12 % R
% Ser: 23 0 0 0 0 0 0 23 0 0 0 0 0 0 12 % S
% Thr: 0 12 0 0 0 0 12 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 23 0 0 12 12 23 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 23 23 0 0 0 12 0 12 23 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _